Protox Biotech

FLAER

FLAER - for the detection of PNH

This variant binds to GPI-anchored proteins like wild type proaerolysin, but it cannot form channels and therefore doesn't cause cell death. The Alexa-488 label it contains is very similar in spectral properties to fluorescein.

FLAER is useful for confocal and flow cytometry studies. Many labs use the reagent routinely for the diagnosis of paroxysmal nocturnal hemoglobinuria by FACS.